Bioinformatics
Getting started guides
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A guide to transcriptomics with Oxford Nanopore
This guide introduces cDNA and direct RNA Oxford Nanopore sequencing, for ultra-rich transcriptomic data without compromise.
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A guide to microbial sequencing with Oxford Nanopore
A guide to get started with sequencing microbial samples with Oxford Nanopore.
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A guide to targeted sequencing with Oxford Nanopore
This guide provides an introduction to performing targeted nanopore sequencing.
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A guide to biopharma solutions from Oxford Nanopore
This guide introduces Oxford Nanopore sequencing solutions for biopharma that can be applied from biomarker discovery through to final product quality control (QC) testing.
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A guide to human genomics with Oxford Nanopore
This guide introduces how to sequence human genomes with Oxford Nanopore, from the construction of new, highly complete reference assemblies to the comprehensive identification of variants.
Workflow overviews
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Characterising genomic and epigenomic variation between tumour-normal research samples using long nanopore sequencing reads
This end-to-end workflow overview provides a simple solution for detecting a wide range of tumour-specific variation in a single sequencing assay.
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Rapid identification of pathogenic variants and methylation with whole-genome Oxford Nanopore sequencing
This end-to-end workflow introduces how to perform rapid whole-genome human variant and methylation calling from a blood research sample using high-output DNA sequencing on PromethION 24.
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Real-time enrichment of a comprehensive pharmacogenomic panel with Oxford Nanopore sequencing
This end-to-end workflow introduces how to enrich a comprehensive panel of PGx targets with real-time targeted Oxford Nanopore sequencing.
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Accelerating clinical research with Oxford Nanopore large cohort sequencing
This end-to-end workflow provides a scalable solution for genome-wide analysis of genomic and epigenomic variants across a large cohort of human research samples with Oxford Nanopore sequencing.
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Comprehensive human genomic variant and methylation analysis with long Oxford Nanopore reads
This end-to-end workflow provides a scalable method to identify previously hidden and potentially pathogenic variants.
Most viewed
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Pharmacogenomic Oxford Nanopore sequencing of the Twist Alliance Long-Read PGx Panel
Discover how the Oxford Nanopore and Twist Bioscience pharmacogenomic research workflow delivers PGx sequencing without compromise.
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Accelerate your epigenetics research with Oxford Nanopore sequencing
In this flyer, find out how Oxford Nanopore sequencing uncovers the complete methylome and provides highly accurate and comprehensive base modification data for analysis.
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Oxford Nanopore 24-hour whole-genome sequencing for paediatric rare disease research
Discover how the Oxford Nanopore rapid whole-genome sequencing workflow is delivering fast, actionable results in 24 hours from sample collection.
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EPI2ME: data analysis for all levels of expertise
Discover EPI2ME and how it provides data analysis for all levels of expertise
Featured resources
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Accelerating cancer research through comprehensive genomic analysis
Unlock previously hidden variation with nanopore sequencing and characterise cancer at unprecedented resolution.
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High-quality bacterial genomes without the complexity
In this case study, researchers show that near-complete bacterial genomes can be assembled using nanopore sequencing alone.
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Wastewater sequencing — an early warning system for infectious disease outbreaks
Monitoring the genomic characteristics of pathogens circulating in a population can reveal important insights into the epidemiological dynamics of an outbreak. Unfortunately, sequencing every confirmed positive sample in a densely populated area is both challenging and expensive. Since viruses are s
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Towards routine modopathy diagnostics: advances and clinical application of direct RNA sequencing | LC 25
BiographyAnna completed her Bachelor’s degree in Biology and specialised in Applied Bioinformatics during her Master’s studies at the Johannes Gutenberg University in Mainz. In 2019, Anna started her PhD at the Leibniz Institute for Resilience.AbstractRNA modification
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Simple, simultaneous detection of epigenetic and genetic variants for insights into disease mechanisms
Methylation has been implicated in the pathogenic mechanisms of many genetic diseases, such as Prader-Willi syndrome1 and fragile X syndrome (FXS)2. However, traditional sequencing methods require the use of amplification, which erases all epigenetic modifications. This means that the presence of me
Analysis workflows
Latest research
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Understanding bacterial DNA methylation and analysis methods
In this webinar we learn how to advance microbial genomics and epigenomics research with authenticated reference resources.
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Sensitive long-read amplicon sequence variant recovery with savont
Publication: Sensitive long-read amplicon sequence variant recovery with savont
Bridging the bioinformatics gap: tool selection for decentralized AMR genomic surveillance in Africa
Publication: Bridging the bioinformatics gap: tool selection for decentralized AMR genomic surveillance in Africa
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Telomere-to-telomere assembly using HERRO-corrected simplex nanopore reads
Publication: Telomere-to-telomere assembly using HERRO-corrected simplex nanopore reads
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Cancer genome standards for long-read sequencing using cancer cell line mixtures
Publication: Cancer genome standards for long-read sequencing using cancer cell line mixtures
