Microbial genetics
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Fully characterise microbial genomes
Microorganisms are the most abundant and diverse forms of life on Earth, with estimates ranging from millions to trillions of species; however, only a small percentage have been identified, let alone sequenced. Of the ~400,000 microbial strains for which sequencing data is available, the majority of genomes are incomplete, reflecting the inherent challenges associated with legacy short-read sequencing technologies.
Combining the ability to sequence any length of DNA or RNA fragment — from short to ultra long (4.2 Mb achieved) — with affordable portable and benchtop devices and real-time results, researchers are using scalable Oxford Nanopore technology to fully characterise microbial diversity for a wide range of applications.
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Bacterial isolate sequencing
The nanopore-only microbial isolate sequencing solution (NO-MISS) is an end-to-end workflow providing a flexible and rapid approach for whole-genome sequencing of bacterial isolates, generating data for a range of applications from public health to clinical microbiology research and use in the biopharma sector.
Pathogen surveillance with Oxford Nanopore sequencing
Infectious disease outbreaks have been a threat throughout human history, and driven by factors such as increasing globalisation, population growth, and climate change, that threat is increasing. See how Oxford Nanopore sequencing delivers comprehensive, affordable, portable, and real-time analysis of pathogens.
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Recommended device for microbiology
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GridION
A compact benchtop device designed to run and analyse up to five MinION Flow Cells. Run multiple microbial sequencing and other projects on a single device — from whole-genome assembly and targeted sequencing to transcriptomics.
