Cancer research

This guide introduces cDNA and direct RNA Oxford Nanopore sequencing, for ultra-rich transcriptomic data without compromise.

This guide provides an introduction to performing targeted nanopore sequencing.

This guide introduces how to sequence human genomes with Oxford Nanopore, from the construction of new, highly complete reference assemblies to the comprehensive identification of variants.

This guide provides an introduction to the direct sequencing of DNA methylation in human genomes.

This guide introduces the single-cell RNA nanopore sequencing workflow, for ultra-rich data without compromise.

In this flyer, discover how to utilise the Oxford Nanopore Hereditary Cancer Panel to investigate 258 key genes associated with hereditary cancer risk.

In this application note, we present the design and performance of the Oxford Nanopore Hereditary Cancer Panel targeting 258 key genes implicated in cancer predisposition.

In this flyer, find out how Oxford Nanopore provides gold-standard methylation sequencing and comprehensive variant calling in a single run — without chemical conversion.

Find out how multiomic nanopore sequencing can accelerate your disease research using a single platform.

Multiply your insights with PromethION 24, the production-scale nanopore sequencer that puts you in control of up to 24 high-output flow cells. Discover more.

This end-to-end workflow provides a scalable method to identify previously hidden and potentially pathogenic variants.

Discover the Hereditary Cancer Panel workflow and streamline your precision oncology research.

This end-to-end workflow provides a flexible method to sequence full-length transcripts for isoform-level expression analysis.

This end-to-end workflow overview provides a simple solution for detecting a wide range of tumour-specific variation in a single sequencing assay.

This end-to-end workflow provides a simple solution for single-cell transcriptome analysis from 10x Genomics cDNA with library preparation in approximately three hours.

Homologous recombination deficiency (HRD) affects breast, ovarian, pancreas and prostate cancers. Patients with HRD tumours can respond to poly ADP-ribose polymerase (PARP) inhibitors and platinum-based therapies. HRD results in a variety of single base, insertion and deletion, and large structural

Timely and comprehensive molecular classification is essential for therapeutic decision-making in pediatric oncology, yet current diagnostic workflows rely on multi-step, time- and resource-intensive testing. We present a standardized Oxford Nanopore Technologies whole-genome sequencing approach usi

Explore the advantages of Oxford Nanopore sequencing to detect genomic and epigenomic variants in human and clinical research.

Unlock previously hidden variation with nanopore sequencing and characterise cancer at unprecedented resolution.

What if targeted sequencing took place during sequencing itself, without the need for special library prep, PCR, or probes? In this demo, discover Adaptive Sampling: a unique, real-time targeted enrichment/depletion method that achieves just that.

This is an end-to-end method outlining sample extraction, library preparation, sequencing, and data analysis.

This protocol describes how to carry out sequencing of a DNA sample using the Ligation Sequencing Kit V14 (SQK-LSK114). It is recommended that a Lambda control experiment is completed first to become familiar with the technology.

This protocol describes how to carry out native barcoding of genomic DNA (gDNA) using the Native Barcoding Kit 24 V14 (SQK-NBD114.24).

This document describes the barcoding of native genomic DNA libraries. For Research Use Only

Learn about Oxford Nanopore's off-the-shelf solutions for creating simple, rapid custom panels providing data-rich scalable insights into cancer biology.

Learn how real-time Oxford Nanopore sequencing results enables rapid methylation classification of tumours.

Authors: Min Seon Park, Erin Crotty, Trent Prall, Miranda PG Zalusky, Jeff Stevens, Vera Paulson, Rebecca Ronsley, Kristyn Galbraith, Joy Goffena, Sophie HR Storz, Zachery B. Anderson, Angela L. Miller, Matthew Snyder, Bonnie Cole, Sarah Leary, Tina Lockwood, Danny Miller

Join us for a deep dive into adaptive sampling, a unique software-based target enrichment method from Oxford Nanopore Technologies.

Presented at AACR 2026, this recording demonstrates how rapid molecular insights can be leveraged to inform clinical decision-making and advance time-critical cancer care.