Whole-genome sequencing

This guide introduces Adaptive Sampling, a unique on-device, real-time targeted sequencing method, providing an enhanced whole-genome view.

This guide introduces Oxford Nanopore sequencing solutions for biopharma that can be applied from biomarker discovery through to final product quality control (QC) testing.

A guide to get started with sequencing microbial samples with Oxford Nanopore.

This guide introduces how to sequence human genomes with Oxford Nanopore, from the construction of new, highly complete reference assemblies to the comprehensive identification of variants.

This guide provides an introduction to the direct sequencing of DNA methylation in human genomes.

This end-to-end workflow provides a scalable method to identify previously hidden and potentially pathogenic variants.

This end-to-end workflow provides a rapid solution for whole-genome Oxford Nanopore sequencing of bacterial and fungal isolates.

This end-to-end workflow provides guidance for both metagenomic and targeted viral genome sequencing to deliver rapid and actionable results.

This end-to-end workflow overview provides a simple solution for detecting a wide range of tumour-specific variation in a single sequencing assay.

This end-to-end workflow introduces how to perform rapid whole-genome human variant and methylation calling from a blood research sample using high-output DNA sequencing on PromethION 24.

In this flyer, discover our tumour methylation solutions to comprehensively profile solid tumours using one of our validated protocols.

In this flyer, discover Mahi-mahi: an analysis tool powered by Oxford Nanopore reads that captures and phases repeat expansion lengths, motifs, sequence interruptions, and methylation in a single assay.

In this brochure, discover Oxford Nanopore sequencing techniques that can reveal multidimensional insights for your microbial research applications.

Find out how multiomic nanopore sequencing can accelerate your disease research using a single platform.

In this application note, we demonstrate the suitability of Oxford Nanopore sequencing as a standalone platform for foodborne pathogen whole-genome sequencing.

Discover how population-scale pangenomes across Asia are improving our understanding of genetic diversity, evolution, and human health.

Timely and comprehensive molecular classification is essential for therapeutic decision-making in pediatric oncology, yet current diagnostic workflows rely on multi-step, time- and resource-intensive testing. We present a standardized Oxford Nanopore Technologies whole-genome sequencing approach usi

Homologous recombination deficiency (HRD) affects breast, ovarian, pancreas and prostate cancers. Patients with HRD tumours can respond to poly ADP-ribose polymerase (PARP) inhibitors and platinum-based therapies. HRD results in a variety of single base, insertion and deletion, and large structural

Discover how a global community of researchers are harnessing Oxford Nanopore sequencing to study the far-reaching impacts of climate change, revealing deep insights across environmental research, agriculture, and pathogen surveillance.

Unlock previously hidden variation with nanopore sequencing and characterise cancer at unprecedented resolution.

This protocol describes how to carry out sequencing of a DNA sample using the Ligation Sequencing Kit V14 (SQK-LSK114). It is recommended that a Lambda control experiment is completed first to become familiar with the technology.

Ultra-Long DNA Sequencing Kit V14 (SQK-ULK114)

This repository contains a nextflow workflow for analysing variation in human genomic data.

This workflow calls variants from the alignment files of a paired tumor/normal sample.

Population-scale long-read whole-genome sequencing of UK Biobank participants using Oxford Nanopore

Evaluation of Oxford Nanopore whole-genome methylation sequencing for phenotype inference and association testing

Analysis tools for resolving challenging medically relevant genes using nanopore whole-genome and digital panel data

Prof. Sebastian Lunke is the Head of Division of Genetics and Genomics at the Victorian Clinical Genetics Services. His team oversees the development and delivery of clinically accredited genetics and genomics laboratories in Australia, with a strong focus on translating...

Presented at AACR 2026, this recording demonstrates how rapid molecular insights can be leveraged to inform clinical decision-making and advance time-critical cancer care.