Clinical research

This guide introduces cDNA and direct RNA Oxford Nanopore sequencing, for ultra-rich transcriptomic data without compromise.

This guide provides an introduction to performing targeted nanopore sequencing.

This guide introduces how to sequence human genomes with Oxford Nanopore, from the construction of new, highly complete reference assemblies to the comprehensive identification of variants.

This guide provides an introduction to the direct sequencing of DNA methylation in human genomes.

This guide introduces the single-cell RNA nanopore sequencing workflow, for ultra-rich data without compromise.

In this flyer, discover how to utilise the Oxford Nanopore Hereditary Cancer Panel to investigate 258 key genes associated with hereditary cancer risk.

In this flyer, discover Mahi-mahi: an analysis tool powered by Oxford Nanopore reads that captures and phases repeat expansion lengths, motifs, sequence interruptions, and methylation in a single assay.

In this flyer, find out how Oxford Nanopore provides gold-standard methylation sequencing and comprehensive variant calling in a single run — without chemical conversion.

Find out how multiomic nanopore sequencing can accelerate your disease research using a single platform.

In this application note, we evaluated the updated Oxford Nanopore cDNA-PCR sequencing protocol updated protocol and compared its performance with that of the previous version of the protocol, Illumina short-read RNA-seq, and Pacific Biosciences Kinnex.

Discover the Hereditary Cancer Panel workflow and streamline your precision oncology research.

This end-to-end workflow introduces how to enrich a comprehensive panel of PGx targets with real-time targeted Oxford Nanopore sequencing.

This end-to-end workflow provides a scalable method to identify previously hidden and potentially pathogenic variants.

This end-to-end workflow provides a simple method to characterise RNA modifications from a human blood research sample using direct RNA sequencing.

This end-to-end workflow provides a rapid solution for whole-genome Oxford Nanopore sequencing of bacterial and fungal isolates.

Discover how population-scale pangenomes across Asia are improving our understanding of genetic diversity, evolution, and human health.

The presenter describes the route to clinical accreditation of Long-read whole genome sequencing (lrWGS) using Oxford Nanopore Technology. Demonstrating accuracy comparable to short-read sequencing across multiple variant types and sample types.

Clinical metagenomics is a rapidly advancing field in infectious disease diagnostics, using next-generation sequencing to identify pathogens directly from clinical samples without prior assumptions. In this presentation, Dr Adela Alcolea-Medina will describe the development, validation, and national

Explore the advantages of Oxford Nanopore sequencing to detect genomic and epigenomic variants in human and clinical research.

What if targeted sequencing took place during sequencing itself, without the need for special library prep, PCR, or probes? In this demo, discover Adaptive Sampling: a unique, real-time targeted enrichment/depletion method that achieves just that.

Este protocolo ofrece un flujo de trabajo completo con el que analizar genes famacogenómicos mediante muestreo adaptativo y la plataforma de Oxford Nanopore.

This document describes the sequencing of adeno-associated viral (AAV) vectors. For Research Use Only

This workflow extracts cell barcodes and UMIs from 10x-generated single cell libraries. It was initially created as a Nextflow port of Sockeye.

This workflow calls variants from the alignment files of a paired tumor/normal sample.

Among other uses this workflow could determine the success of a molecular cloning experiment and determine whether one DNA sequence has been correctly inserted into another as an experimentalist was expecting.

This workflow takes reads sequenced from adeno-associated virus (rAAV) vector preps and does some basic quality control checks.

Analysis tools for resolving challenging medically relevant genes using nanopore whole-genome and digital panel data

Join us for a deep dive into adaptive sampling, a unique software-based target enrichment method from Oxford Nanopore Technologies.

Prof. Sebastian Lunke is the Head of Division of Genetics and Genomics at the Victorian Clinical Genetics Services. His team oversees the development and delivery of clinically accredited genetics and genomics laboratories in Australia, with a strong focus on translating...

Learn about Oxford Nanopore's off-the-shelf solutions for creating simple, rapid custom panels providing data-rich scalable insights into cancer biology.

Authors: Luca Morandi, Francesco Casadei, Sara De Fanti, Luigi Bonan, Francesco Ravaioli, Flavia Palombo, Alessia Fiorentino, Silvia de Pasqua, Veria Vacchiano, Patrizia Avoni, Giovanni Rizzo, Sabina Capellari, Edoardo Ruggeri, Vincenzo Donadio, Gastone Castellani, Maria Giulia Bacali