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Software release 2.0.1 for Dorado

Version: 2.0.1

Release date: 6/15/2026

Approved use: For research use only

  • Dorado basecaller command now adds a @PG ID:aligner header line
  • Fix "bad any_cast" error when using modified-bases-threshold argument
  • Fix Dorado duplex command when running DNA HAC v6.0.0 model
  • Fix MD5 sums for M5 tags to conform to the SAM spec
  • Only create poly(A) worker threads when poly(A) estimation is enabled
  • Add initial MPS backend implementation for v6.0.0 HAC on MacOS
  • Add pre-computed batch size benchmarks for Quadro GV100
  • Add pre-computed batch size benchmarks for RTX PRO 6000 variants, H100 PCIe, RTX A6000, RTX 5070 Ti and RTX 5090
  • Fix a crash when running v6.0.0 HAC models on Win/Linux hosts that do not have NVIDIA drivers installed, when using CPU mode

Last updated: 6/15/2026

Latest version: 2.0.1

Approved use: For research use only

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