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Dorado

High-performance, easy-to-use commandline basecaller for Nanopore data. Developer release for evaluation of new features. For information about the Dorado project, see https://github.com/nanoporetech/dorado.

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Dorado documentation
For more detailed advice, documentation and installation guides for Dorado

Version: 2.0.1

Release date: 6/15/2026

Approved use: For research use only

  • Dorado basecaller command now adds a @PG ID:aligner header line
  • Fix "bad any_cast" error when using modified-bases-threshold argument
  • Fix Dorado duplex command when running DNA HAC v6.0.0 model
  • Fix MD5 sums for M5 tags to conform to the SAM spec
  • Only create poly(A) worker threads when poly(A) estimation is enabled
  • Add initial MPS backend implementation for v6.0.0 HAC on MacOS
  • Add pre-computed batch size benchmarks for Quadro GV100
  • Add pre-computed batch size benchmarks for RTX PRO 6000 variants, H100 PCIe, RTX A6000, RTX 5070 Ti and RTX 5090
  • Fix a crash when running v6.0.0 HAC models on Win/Linux hosts that do not have NVIDIA drivers installed, when using CPU mode
Release NoteRelease history

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