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Assembly

Generate highly contiguous genome assemblies

High-quality genome assemblies are crucial for their use as reliable reference sequences. However, the short reads produced by legacy sequencing technologies lead to highly fragmented, incomplete assemblies. Short reads cannot span important genomic regions, such as repeats and structural variants (SVs), resulting in incorrect assembly. In contrast, Oxford Nanopore technology can deliver long and ultra-long sequencing reads (current record >4 Mb) that can span complex and repeat-rich genomic regions, enabling the generation of highly contiguous reference-quality genome assemblies.

Using Oxford Nanopore sequencing alone, it is now possible to generate complete telomere-to-telomere (T2T) assemblies, including highly accurate Q50 whole human genomes. Register your interest in our T2T product bundle.

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