Lorne Cancer 2024
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Oxford Nanopore Technologies will be at the Lorne Cancer 2024 conference. The 2024 conference will explore functional genomics of cancer, tumour heterogeneity and evolution, immunotherapy of cancer, the tumour microenvironment, and other key themes such as Paediatric and adult brain tumours, cancer dependencies and functional genomics breast cancer genomics, and oncology translational research.
Join us for our Workshop on Saturday 10th January. See workshop registration details below.
Workshop Registration
Workshop
Nanopore sequencing: what you're missing matters
Date: Saturday 10th January 2024
Time: 2:30pm - 3:30pm
Location: Heritage Dining Room, Mantra Lorne
Martin Smith, UNSW Sydney
Robert Day, University of Otago, Dunedin
Rebecca Chesterfield, Oxford Nanopore Technologies
Speakers & Abstracts
The characterization of somatic mutations through genome sequencing of tumors has revolutionized cancer research, playing a crucial role in understanding tumorigenesis, tumour heterogeneity and identifying potentially actionable targets. To date, the majority of cancer genome studies have been conducted using short-read sequencing. Long-read sequencing using the Oxford Nanopore Technologies (ONT) enables direct sequencing of DNA allowing simultaneous whole genome sequencing and methylation profiling. In this talk, we will share our experiences of long read whole genome analysis to evaluate several approaches for mutation detection and cytosine methylation profiling.
The characterization of somatic mutations through genome sequencing of tumors has revolutionized cancer research, playing a crucial role in understanding tumorigenesis, tumour heterogeneity and identifying potentially actionable targets. To date, the majority of cancer genome studies have been conducted using short-read sequencing. Long-read sequencing using the Oxford Nanopore Technologies (ONT) enables direct sequencing of DNA allowing simultaneous whole genome sequencing and methylation profiling. In this talk, we will share our experiences of long read whole genome analysis to evaluate several approaches for mutation detection and cytosine methylation profiling.
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Martin Smith, UNSW SydneyHere I’ll present work that aims to develop multimodal approaches for ctDNA profiling in cancers. We take a look at our ability to profile ctDNA from Breast cancer and CRC samples and efforts to implement different strategies to improve early disease detection via improved base calling accuracy and profiling multiple different layers of biological information.
Here I’ll present work that aims to develop multimodal approaches for ctDNA profiling in cancers. We take a look at our ability to profile ctDNA from Breast cancer and CRC samples and efforts to implement different strategies to improve early disease detection via improved base calling accuracy and profiling multiple different layers of biological information.
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Robert Day, University of Otago
