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At NCM, announcements include single-read accuracy of 99.1% on new chemistry and sequencing a record 10 Tb in a single PromethION run

3rd December 2020

During an update at the 2020 Nanopore Community Meeting, Oxford Nanopore revealed a number of key advances in its sequencing technology. These include the release of new improvements in PromethION ...

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Two new papers further demonstrate the role adaptive sampling could play in understanding genetic disease

30th November 2020

Two new papers published in Nature Biotech today, from teams at the University of Nottingham and Johns Hopkins University, demonstrate the use of real-time nanopore sequencing and adaptive sampling ...

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Introducing the new MinKNOW App

25th November 2020

Today marks the release of the MinKNOW App for iOS and Android devices, now available to download from the Apple Store and Google Play. MinKNOW is the operating software that drives nanopore sequen...

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Structural variation & cancer: top 7 things to read right now

20th November 2020

Somatic mutations are the driving force behind cancer development, and structural variations (SVs) are more and more being recognised as an important class of these mutations. The detection of SVs i...

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Interview: Nanopore sequencing: the mobile methylome

17th November 2020

Adam Ewing leads the Translational Bioinformatics Group at the Mater Research Institute - University of Queensland in Australia, where he works to develop methods and software for analysing high t...

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Structural variation in human genomics: 6 things to read right now

3rd November 2020

The significance of structural variation in human genomics is becoming increasingly established in many fields, from cancer to neurology and the mechanisms of rare disease. With research moving at a...

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Epigenetics, Cas9-mediated enrichment and novel insights in transcriptome variation: catch up on talks from ASHG 2020

30th October 2020

This week we heard from Ariel Gershman, Shruti Iyer and Tuuli Lappalainen on their latest research addressing some of the key challenges in human genomics using nanopore technology. The talks are no...

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Oxford Nanopore announces multiple releases, for high-accuracy, content-rich, high-throughput whole-genome sequencing, and dynamic targeted sequencing

28th October 2020

- announced at the 2020 American Society of Human Genetics (ASHG) Meeting. Oxford, UK, 28th October 2020. Oxford Nanopore announces multiple releases that expand and improve its sequencing techno...

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Your Oxford Nanopore guide to ASHG 2020 online

26th October 2020

ASHG 2020 has moved online this year but there’s still plenty going on and lots of ways you can find out about how human genomics researchers are overcoming some of the big challenges in the field...

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Blog: cuteSV - a powerful tool to uncover the full spectrum of genomic structural variants

19th October 2020

In this blog, Tao Jiang describes his work on the development of the structural variant (SV) caller cuteSV. Read on to find out how the cuteSV bioinformatics pipeline works, how it performs relative...

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Oxford Nanopore announces £84.4M in new capital

13th October 2020

Oxford, UK: Oxford Nanopore Technologies has raised £84.4M in new capital. The funding comes from existing investors and new investors, including International Holdings Company (IHC), RPMI Railpen...

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Oxford Nanopore, the Bill and Melinda Gates Foundation, Africa Centres for Disease Control and Prevention and other partners collaborate to transform disease surveillance in Africa

12th October 2020

Oxford Nanopore, the Bill & Melinda Gates Foundation, US CDC, Microsoft and Illumina collaborate with the Africa Centres for Disease Control and Prevention (Africa CDC) to launch Africa Pathogen...

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LamPORE test for SARS-CoV-2 detection gains CE-IVD mark

9th October 2020

LamPORE is a new, rapid, scalable, accurate test, for the detection of the SARS-CoV-2 virus that causes COVID-19. LamPORE is designed to be performed on a desktop device, GridION, or a palm-sized de...

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Interview: Improving structural variant interpretation for hereditary cancer susceptibility

5th October 2020

Accurate molecular diagnosis of cancer-causing germline variants enables increased screening, early detection, prevention, and optimal treatment, if cancer does arise in predisposed patients and t...

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Oxford Nanopore welcomes Dr Guy Harmelin as a non-executive Director

2nd October 2020

Guy has extensive experience in healthcare and technology investment and entrepreneurship. He was previously on the leadership team at Harel Insurance Investments and Financial Services, the largest...

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Blog: Copy number variation analysis from plasma: is it feasible using nanopore sequencing?

29th September 2020

In this blog, Filippo Martignano shares his research into copy number variation (CNV) analysis in cancer, from cell-free DNA samples, using shallow whole-genome sequencing. Read on to hear why he ch...

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LamPORE evaluation study shows 99.1% sensitivity, 99.6% specificity

25th September 2020

Scientists from the University of Oxford’s Nuffield Department of Medicine, Public Health England Porton Down (PHE), the University of Sheffield, Sheffield Teaching Hospitals NHS Foundation Trust ha...

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Targeted sequencing with Oxford Nanopore: Fast, flexible, PCR-free Cas9 Sequencing Kit now available in store

16th September 2020

New Cas9 Sequencing Kit provides reagents for one-stop targeted sequencing, enabling scientists to cost-effectively sequence previously inaccessible target regions. Cas9 targeted sequencing with...

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Blog: Resolving structural variants causing antithrombin deficiency

14th September 2020

In this blog, Alba Sanchis-Juan, Javier Corral, and Belén de la Morena-Barrio describe their research into the genetic basis of thrombophilia, and how nanopore long sequencing reads were needed to r...

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Blog: Revealing the impact of structural variants on cancer susceptibility

2nd September 2020

In this blog, Katherine Dixon shares her team’s work on identifying structural variants in cancer genomes, and she explains why identifying them accurately is so important. Katherine DixonI am a...

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Oxford Nanopore Technologies partners with UK Government to roll out LamPORE, a new generation of COVID-19 test

3rd August 2020

Ground-breaking British technology will initially provide hundreds of thousands of fast, accurate, low-cost COVID-19 tests under new agreement with the UK Government, with the potenti...

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First complete assembly of human X chromosome

15th July 2020

The first telomere-to-telomere human chromosome was published in Nature this week — a landmark achievement for genomics researchers. Lead author Karen Miga, from the UC Santa Cruz Genomics Institut...

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Interview: Identification of structural variation in chimpanzees using optical mapping and nanopore sequencing

10th July 2020

Daniela Soto is a Ph.D. candidate in the Integrative Genetics and Genomics program at UC Davis, working in the Dennis Lab where she is using long-read sequencing technologies to unveil the variabi...

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LamPORE for SARS-CoV-2 detection: the science behind the new assay

20th June 2020

LamPORE is a new assay, in advanced development at Oxford Nanopore. It is designed to detect the presence of SARS-CoV-2, the virus that causes COVID-19, in a saliva, swab or environmental samples. ...

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