Oxford Nanopore Support
Support
- Home
- Support
- Library prep
- General Lab Practice
- HOW DO I PREVENT DNA SHEARING DURING LIBRARY PREPARATION
How do I prevent DNA shearing during library preparation?
How do I prevent DNA shearing during library preparation?
To preserve long-lengths of DNA input/libraries we recommend mixing your sample and reagents very gently. Use of wide-bore pipette tips will also assist in mitigating DNA shearing during your sample and library preparation. Additionally, always follow the sample storage recommendations in our documentation for optimal results.