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Sequencing ultra-long DNA molecules with the Oxford Nanopore MinION


Oxford Nanopore Technologies’ nanopore sequencing device, the MinION, holds the promise of sequencing ultra-long DNA fragments >100kb. An obstacle to realizing this promise is delivering ultra-long DNA molecules to the nanopores. We present our progress in developing cost-effective ways to overcome this obstacle and our resulting MinION data, including multiple reads >100kb.

Authors: John M Urban, Jacob Bliss, Charles E Lawrence, Susan A Gerbi

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