A guide to targeted sequencing with Oxford Nanopore
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- Published on: February 10 2026
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Targeted sequencing enables regions of interest to be analysed in a cost-effective and fast workflow, which is beneficial for applications where whole-genome sequencing is inefficient or costly. Combining innovative enrichment methods with real-time sequencing, nanopore technology provides significant advantages over conventional targeted sequencing methodologies.
In this getting started guide, learn about digital panels and how they are powered by Adaptive Sampling to perform targeted nanopore sequencing during a live sequencing run without PCR or additional library preparation.
In this getting started guide, you will:
- Find out how Adaptive Sampling enhances targeted nanopore sequencing by enriching or depleting regions of interest
- Discover the benefits of nanopore sequencing
- Identify the appropriate nanopore sequencing kit for your experiment
- For any questions, see the FAQs for this technique
- Read real-world case studies of how researchers are utilising nanopore sequencing to perform targeted analysis and generate high-quality data, including how scientists used digital panels to identify deep intronic variants in tumour-supressor genes
