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Nanopore sequencing offers advantages in all areas of research. Our offering includes DNA sequencing, as well as RNA and gene expression analysis and future technology for analysing proteins.

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Product specifications

Platform overview Versatile applications Tuneable run settings
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Full biology from a single experiment

Nanopore sequencing is a universal technology capable of resolving small to large genomic variants and aberrations in single loci to whole genomes, from individual samples to population-scale analyses. By sequencing native DNA fragments, from 20 bases in length to millions of bases, this single, accurate, and accessible technology provides a comprehensive insight into the true biology present than any other sequencing technology. Follow the links below to read more

Run one platform at the scale you need

Choose your flow cell type

Flongle Logo Flongle flow cell

126 channels

TMO 2.8 Gb

Suitable for:

  • Library QC
  • Plasmid, viral and bacterial sequencing
  • Low-cost, disposable flow cell from $90
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MinION Logo MinION flow cell

512 channels

TMO 50 Gb

Suitable for:

  • 10-20 Gb of Ultra-long reads
  • Multiplex small genomes
  • Low-pass sequencing of larger genomes
  • From $500
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PromethION Logo PromethION flow cell

2,675 channels

TMO 290 Gb

Suitable for:

  • The highest output flow cells for nanopore sequencing
  • Sequence large genomes to high coverage
  • From $600
Visit store
Flongle Logo Flongle flow cell

126 channels

TMO 2.8 Gb

Suitable for:

  • Library QC
  • Plasmid, viral and bacterial sequencing
  • Low-cost, disposable flow cell from $90
Visit store
MinION Logo MinION flow cell

512 channels

TMO 50 Gb

Suitable for:

  • 10-20 Gb of Ultra-long reads
  • Multiplex small genomes
  • Low-pass sequencing of larger genomes
  • From $500
Visit store
PromethION Logo PromethION flow cell

10,700 channels

TMO 290 Gb

Suitable for:

  • The highest output flow cells for nanopore sequencing
  • Sequence large genomes to high coverage
  • From $600
Visit store

Choose the right device for you

MinION

MinION Mk1B

MinION Mk1C

MinION Mk1C

GridION

GridION

MinION and Flongle Flow Cell compatible

P2 Solo

P2 Solo

P2

P2

PromethION 24

PromethION 24

PromethION 48

PromethION 48

PromethION Flow Cell compatible

Configuration Platform Techniques Tech specifications

Number of flow cells per device

1

1

5

2

2

24

48

Maximum number of channels per flow cell

512

512

512

2,675

2,675

2,675

2,675

Run time

72 Hours

72 Hours

72 Hours

72 Hours

72 Hours

72 Hours

72 Hours

Device TMO
Theoretical max output when system is run for 72 hours at 420 bases / second with all flow cells sequencing. Outputs may vary according to library type, run conditions, etc.

50 Gb

50 Gb

250 Gb

580 Gb

580 Gb

~7 Tb

~14 Tb

Maximum number of flow cells per year
*72 hours per run, 2 complete runs per week, 52 weeks per year.

104

104

520

208

208

2,596

4,992

Offer sequencing as a service

No

No

Yes

Yes

Yes

Yes

Yes

Read length

Nanopores read the entire length of the fragment of DNA/RNA presented to them. Longest read so far: > 4Mb. Accuracy is maintained throughout the fragment.

Single molecule accuracy

Kit 14 Chemistry > Q20 (99%) for Simplex reads, ~Q30 (99.9%) for Duplex reads. Read more on our accuracy page

Consensus accuracy

Please see our accuracy page for a full explanation of platform performance

Sample prep time

Rapid Kit: 10 minutes, Ligation Kit: 60 minutes, other protocols and timings also available

Modified base detection

Yes - Base modification information available in raw signal

Requirement for PCR in sample prep

No

Time to first useable data

2 minutes

WGS - small genomes

Yes: Low to medium plex

Yes: Low to medium plex

Yes: Low to medium plex

Yes: Highly multiplexed

Yes: Highly multiplexed

Yes: Highly multiplexed

Yes: Highly multiplexed

WGS - large genomes

Low pass

Low pass

Yes

Yes

Yes

Yes

Yes

Targeted sequencing

Yes: Low to medium plex, and adaptive sampling

Yes: Highly multiplexed

Metagenomics

Yes: Quantitative species ID

Yes: Quantitative species ID

RNA sequencing

Yes: Isoform & expression from same experiment

Yes: Isoform & expression from same experiment, including low abundance transcripts

Epigenetics

Yes - when native DNA used

Yes - when native DNA used

Power requirement

Powered by laptop

25 W

800 W

N/A

N/A

2.2 kW

2.2 kW

Dimensions

W 105
H 23
D 33 mm

W 140
H 30
D 116 mm

W 365
H 220
D 360 mm

N/A

Sequencer:
W 590
H 190
D 430 mm;

Data Acquisition unit:
W 178
H 440
D 470 mm

Weight

87 g

450 g

11 Kg

N/A

Sequencer: 28 Kg
Data Acquisition unit: 25 Kg

Connectivity

None

Ethernet, MicroSD, USB

1 Gb Ethernet

N/A

Dual 10 Gb Fibre or Ethernet

Storage

None

1 TB SSD

4 TB SSD

N/A

60 TB SSD

RAM

None

8 GB

64 GB

N/A

512 GB

MinION

MinION Mk1B

MinION Mk1C

MinION Mk1C

GridION

GridION

MinION and Flongle Flow Cell compatible

Configuration Platform Techniques Tech specifications

Number of flow cells per device

1

1

5

Maximum number of channels per flow cell

512

512

512

Run time

72 Hours

72 Hours

72 Hours

Device TMO
Theoretical max output when system is run for 72 hours at 420 bases / second with all flow cells sequencing. Outputs may vary according to library type, run conditions, etc.

50 Gb

50 Gb

250 Gb

Maximum number of flow cells per year
*72 hours per run, 2 complete runs per week, 52 weeks per year.

104

104

520

Offer sequencing as a service

No

No

Yes

Read length

Nanopores read the entire length of the fragment of DNA/RNA presented to them. Longest read so far: > 4Mb. Accuracy is maintained throughout the fragment.

Single molecule accuracy

Kit 14 Chemistry > Q20 (99%) for Simplex reads, ~Q30 (99.9%) for Duplex reads. Read more on our accuracy page

Consensus accuracy

Please see our accuracy page for a full explanation of platform performance

Sample prep time

Rapid Kit: 10 minutes, Ligation Kit: 60 minutes, other protocols and timings also available

Modified base detection

Yes - Base modification information available in raw signal

Requirement for PCR in sample prep

No

Time to first useable data

2 minutes

WGS - small genomes

Yes: Low to medium plex

WGS - large genomes

Low pass

Low pass

Yes

Targeted sequencing

Yes: Low to medium plex, and adaptive sampling

Metagenomics

Yes: Quantitative species ID

RNA sequencing

Yes: Isoform & expression from same experiment

Epigenetics

Yes - when native DNA used

Power requirement

Powered by laptop

25 W

800 W

Dimensions

W 105
H 23
D 33 mm

W 140
H 30
D 116 mm

W 365
H 220
D 360 mm

Weight

87 g

450 g

11 Kg

Connectivity

None

Ethernet, MicroSD, USB

1 Gb Ethernet

Storage

None

1 TB SSD

4 TB SSD

RAM

None

8 GB

64 GB

P2 Solo

P2 Solo

P2

P2

PromethION 24

PromethION 24

PromethION 48

PromethION 48

PromethION Flow Cell compatible

Configuration Platform Techniques Tech specifications

Number of flow cells per device

2

2

24

48

Maximum number of channels per flow cell

2,675

2,675

2,675

2,675

Run time

72 Hours

72 Hours

72 Hours

72 Hours

Device TMO
Theoretical max output when system is run for 72 hours at 420 bases / second with all flow cells sequencing. Outputs may vary according to library type, run conditions, etc.

580 Gb

580 Gb

~7 Tb

~14 Tb

Maximum number of flow cells per year
*72 hours per run, 2 complete runs per week, 52 weeks per year.

208

208

2,596

4,992

Offer sequencing as a service

Yes

Yes

Yes

Yes

Read length

Nanopores read the entire length of the fragment of DNA/RNA presented to them. Longest read so far: > 4Mb. Accuracy is maintained throughout the fragment.

Single molecule accuracy

Kit 14 Chemistry > Q20 (99%) for Simplex reads, ~Q30 (99.9%) for Duplex reads. Read more on our accuracy page

Consensus accuracy

Please see our accuracy page for a full explanation of platform performance

Sample prep time

Rapid Kit: 10 minutes, Ligation Kit: 60 minutes, other protocols and timings also available

Modified base detection

Yes - Base modification information available in raw signal

Requirement for PCR in sample prep

No

Time to first useable data

2 minutes

WGS - small genomes

Yes: Highly multiplexed

Yes: Highly multiplexed

Yes: Highly multiplexed

Yes: Highly multiplexed

WGS - large genomes

Yes

Yes

Yes

Yes

Targeted sequencing

Yes: Highly multiplexed

Metagenomics

Yes: Quantitative species ID

RNA sequencing

Yes: Isoform & expression from same experiment, including low abundance transcripts

Epigenetics

Yes - when native DNA used

Power requirement

N/A

N/A

2.2 kW

Dimensions

N/A

N/A

Sequencer:
W 590
H 190
D 430 mm;

Data Acquisition unit:
W 178
H 440
D 470 mm

Weight

N/A

N/A

Sequencer: 28 Kg
Data Acquisition unit: 25 Kg

Connectivity

N/A

N/A

Dual 10 Gb Fibre or Ethernet

Storage

N/A

N/A

60 TB SSD

60 TB SSD

RAM

N/A

N/A

512 GB

512 GB

Versatile applications

Users can choose how to run their experiments to generate the data type they need to answer their biological question.

Regardless of the way users choose to buy and run the technology, high data outputs with transparent consumable pricing delivers great value.

A universal technology

Short fragment mode

Highest read counts

Best for:

  • Fragments down to 20 bases in length
  • Applications such as cDNA
  • Modified base information as standard

Standard fragment mode

Highest yields

Best for:

  • Maximising total Gbase output
  • Read N50s 5-30kb
  • Flexible and adaptable applications
  • Modified base information as standard

Ultra-long sequencing

Longest reads

Best for:

  • The most complete assemblies of large genomes
  • Read N50s > 50kb, reads up to 4 Mbases
  • Modified base information as standard

RNA sequencing

Full-length transcripts

Best for:

  • Single cell sequencing
  • Known and novel transcript ID
  • Isoform detection
Short fragment mode Standard mode Ultra-long sequencing RNA sequencing Cost per Gbase - Standard Cost per Gbase - SFM Cost per Gbase - Ultra-long reads Cost per Gbase - cDNA sequencing

Tuneable run settings

  • Chemistry 14 unifies nanopore sequencing into a single, tuneable chemistry using:
    • Kit 14 sequencing chemistry
    • The R10.4.1 nanopore
    • Tuneable run parameters through temperature
  • Selecting the temperature at which sequencing takes place allows you to tune output and accuracy to best suit your biological answer.
Cooler Sequencing temperature Warmer
Slower translocation speed through the pore
Highest single molecule accuracy (>99.5% modal)
Lower yields

Suited for:

Targeted sequencing for specific SNVs

Middling translocation speed through the pore
Middling single molecule accuracy (>99.3% modal)
Improved yields

Suited for:

Data generation for genome assembly

Fastest translocation speed through the pore
Lower single molecule accuracy (>99% modal)
Highest yields

Suited for:

Transcriptomics

Kit14 Speed Simplex accuracy