Resource Centre
2369 results
Long-read DNA and cDNA sequencing identify cancer-predisposing deep intronic variation in tumour-suppressor genes
- Cancer research
- Targeted
- cDNA
- DNA
- PromethION
September 13 2024
ROBIN: a unified nanopore-based sequencing assay integrating real-time, intraoperative methylome classification and next-day comprehensive molecular b
- Cancer research
- Methylation
- PromethION
- MinKNOW
- Targeted
- Adaptive sampling
September 11 2024
Multi-pass, single-molecule nanopore reading of long protein strands
- Protein
- MinION
- MinKNOW
September 11 2024
Scywalker: scalable end-to-end data analysis workflow for long-read single-cell transcriptome sequencing
- Single cell
- Transcriptome
- Transcriptomics
- Workflow
- Scalable
- Long-read
- cDNA
- PromethION
- Guppy
September 10 2024
Targeted long-read sequencing as a single assay improves diagnosis of spastic-ataxia disorders
- Targeted
- Human genomics
- Clinical research
- Long-read
- Variant calling
- Structural variation
- Splice variation
- PromethION
September 6 2024
Glioblastoma, IDH-wildtype with primarily leptomeningeal localisation diagnosed by nanopore sequencing of cell-free DNA from cerebrospinal fluid
- Cancer research
- cfDNA
- Methylation
September 3 2024
Sensitivity and specificity of nanopore sequencing for detecting carbapenem and 3rd-generation cephalosporin-resistant Enterobacteriaceae in urine s
- Microbiology
- Targeted
- MinKNOW
- Guppy
- Clinical research
August 30 2024
Genetic regulation of nascent RNA maturation revealed by direct RNA nanopore sequencing
- Human genomics
- RNA
- mRNA
- Splice variation
- MinION
- P2 Solo
- MinKNOW
August 29 2024
Discovery of NRG1-VII: the myeloid-derived class of NRG1
- Human genomics
- Transcriptomics
- Targeted
- cDNA
- GridION
August 29 2024
Chromosome-level genome assembly and methylome profile enables insights for the conservation of endangered loggerhead sea turtles
- Animal
- Whole genome
- Conservation
- Methylation
- PromethION
- Guppy
August 28 2024
Exploring the transcriptomic profile of human monkeypox virus via CAGE and native RNA sequencing approaches
- Infectious disease
- RNA
- Transcriptomics
- Transcriptome
- MinION
- Guppy
August 27 2024
Accurate long-read transcript discovery and quantification at single-cell, pseudo-bulk and bulk resolution with Isosceles
- Single cell
- Transcriptomics
- Neuroscience
- PromethION
- MinION
August 25 2024
Advancing long-read nanopore genome assembly and accurate variant calling for rare disease detection
- Human genomics
- Whole genome
- PromethION
- Clinical research
August 22 2024
Transcriptome profiling of paediatric extracranial solid tumours and lymphomas enables rapid low‑cost diagnostic classification
- Cancer research
- Transcriptomics
- MinION
- P2
- Guppy
August 21 2024
Integrative analysis of long isoform sequencing and functional data identifies distinct cortical layer neuronal subtypes derived from human iPSCs
- Human genomics
- Single cell
- Neuroscience
- Long-read
- PromethION
- Guppy
August 21 2024
Extraction of high-molecular-weight DNA from Streptococcus spp. for nanopore sequencing in resource-limited settings
- Microbiology
- Infectious disease
- MinION
- Bacteria
- EPI2ME
August 21 2024
Adapting nanopore sequencing basecalling models for modification detection via incremental learning and anomaly detection
- Bioinformatics
- DNA
- RNA
- Methylation
August 21 2024
Rapid whole genome characterisation of high-risk pathogens using long-read sequencing to identify potential healthcare transmission
- Infectious disease
- Whole genome
- MinION
- Real-time
August 20 2024
FindingNemo: A toolkit for DNA extraction, library preparation and purification for ultra-long nanopore sequencing
- Long-read
- GridION
- PromethION
- MinKNOW
August 19 2024