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London Calling 2024 - Speakers

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Oxford Nanopore Technologies

Morghan Lucas

Morghan Lucas
Job title
Institution
Medical Genetics Center, Germany
Biography

Morghan Lucas is the co-lead of R&D at the Medical Genetics Centre (MGZ) Munich and a research scientist at the Ludwig Maximilian University of Munich (LMU). Her primary research focuses on developing molecular diagnostic tests for various diseases, including hereditary cancers and muscular dystrophy, with an emphasis on sequencing technologies. Prior to this, Morghan obtained her PhD at the Centre for Genomic Regulation (CRG) under the guidance of Dr. Eva Maria Novoa, where she developed various direct RNA nanopore sequencing-based methods for RNA modification detection, short RNA sequencing, and multiplexing.

Recent publications

Lucas, M.C. et al. Quantitative analysis of tRNA abundance and modifications by nanopore RNA sequencing. Nat. Biotechnol. 42:72–86 (2024). DOI:10.1038/s41587-023-01743-6.

Begik, O. et al. Quantitative profiling of pseudouridylation dynamics in native RNAs with nanopore sequencing. Nat. Biotechnol. 39:1278–129 (2021). DOI:10.1038/s41587-021-00915-6

Milenkovic, I. et al. Dynamic interplay between RPL3- and RPL3L-containing ribosomes modulates mitochondrial activity in the mammalian heart. Nucleic Acids Research 51(11):5301–5324 (2023). DOI:10.1093/nar/gkad121

Talks at this conference