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Oxford Nanopore Technologies

Hagan Bayley

Hagan Bayley
Job title
Institution
University of Oxford, UK
Biography

Hagan Bayley is the Professor of Chemical Biology at the University of Oxford. A major interest of his laboratory is the development of engineered protein nanopores for stochastic detection, including single- molecule covalent chemistry and ultrarapid biopolymer sequencing. Recently, the Bayley laboratory has developed techniques for the fabrication of 3D tissues, both living and synthetic. In 2005, Professor Bayley founded Oxford Nanopore, which has manufactured the portable MinION and other DNA/RNA sequencers.

Recent publications

Qing, Y. and Bayley, H. Enzymeless DNA base identification by chemical stepping in a nanopore. J Am Chem Soc. 143(43):18181–18187 (2021). DOI: https://doi.org/10.1021/jacs.1c07497

Martin-Baniandres, P., et al. Enzyme-less nanopore detection of post-translational modifications within long polypeptides. Nat. Nanotechnology. 18:1335–1340 (2023). DOI: https://doi.org/10.1038/s41565-023-01462- 8

Lan, W., He, H., Bayley, H., and Qing, Y. Location of phosphorylation sites within long polypeptide chains by binder-assisted nanopore detection. bioRxiv (2024) DOI: https://www.biorxiv.org/content/10.1101/2024.04.29.590540v1

Talks at this conference