A multi-omics approach to characterise epithelial to mesenchymal transition in lung cancer metastasis

Evaluate cells undergoing the phenotypic transition from epithelial to mesenchymal states using full-length transcriptomics, targeted methylation, and chromatin conformational changes with Pore-C.

Download the poster to discover:

  • The morphological changes underlying epithelial-mesenchymal transition (EMT) in cancer cells
  • How to perform a multi-omic analysis of the EMT process in cancer, from the generation of whole-genome, transcriptome, and Pore-C nanopore sequence data
  • How to use differential transcript expression analysis and Pore-C chromatin conformation capture data to understand genomic changes involved in tumour metastasis
  • How to use adaptive sampling to explore methylation differences at EMT loci

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